Clinical characteristics of acute promyelocytic leukemia manifesting as early death
نویسندگان
چکیده
منابع مشابه
Clinical characteristics of acute promyelocytic leukemia manifesting as early death
Acute promyelocytic leukemia (APL) is currently considered to be a highly curable disease. However, early death (ED) remains a major cause of treatment failure in APL. The purpose of this study was to retrospectively review the morphological, immunophenotypic and molecular characteristics of 26 patients with APL resulting in ED. It was observed that elevated white blood cell (WBC) counts, lower...
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With the introduction of all-trans retinoic acid (ATRA) and arsenic trioxide, acute promyelocytic leukemia (APL) has become a highly curable malignancy. Approximately 90% of patients achieve complete remission with induction, which generally includes ATRA and an anthracycline-based chemotherapy. Early death, either before treatment is initiated or during induction, has emerged as one of the mos...
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ژورنال
عنوان ژورنال: Molecular and Clinical Oncology
سال: 2013
ISSN: 2049-9450,2049-9469
DOI: 10.3892/mco.2013.155